Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NMT2 | O60551 | 2/20 | 0.42 |
| ▸ | NMT1 | P30419 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476964 | 0.86 | NMT1 (0.57) | NMT2NMT1KDM4E | |
| SCHEMBL6870953 | 0.84 | NMT2 (0.52) | NMT2NMT1 | |
| SCHEMBL6863650 | 0.83 | MAOA (0.44) | PKMMAPTNMT2NMT1KMT2A | |
| SCHEMBL6863212 | 0.82 | NMT2 (0.42) | NMT2NMT1DRD2DRD4DRD3 | |
| SCHEMBL6870905 | 0.74 | MAOB (0.49) | NMT2NMT1KMT2AKDM4EMAOB | |
| SCHEMBL6874419 | 0.73 | NMT2 (0.75) | NMT2NMT1 | |
| SCHEMBL6868611 | 0.73 | NMT2 (0.64) | NMT2NMT1 | |
| SCHEMBL6873152 | 0.72 | NMT2 (0.55) | NMT2NMT1 | |
| SCHEMBL6871597 | 0.72 | NMT2 (0.55) | NMT2NMT1 | |
| SCHEMBL6863714 | 0.72 | NMT2 (0.55) | NMT2NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | claimed |