Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | NMT2 | O60551 | 1/20 | 0.48 |
| ▸ | NMT1 | P30419 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870953 | 0.91 | NMT2 (0.52) | NMT2NMT1BACE1 | |
| SCHEMBL6870343 | 0.91 | NMT2 (0.46) | MAOBBCHEACHENMT2NMT1 | |
| SCHEMBL6870460 | 0.87 | MAOB (0.49) | MAOBBCHEACHEBACE1 | |
| SCHEMBL6869318 | 0.87 | NMT2 (0.65) | MAOBBCHEACHENMT2NMT1 | |
| SCHEMBL6863786 | 0.81 | KDM4E (0.49) | MAOBBCHEACHENMT2NMT1 | |
| SCHEMBL6863415 | 0.80 | NMT2 (0.72) | NMT2NMT1 | |
| SCHEMBL6863219 | 0.78 | NMT2 (0.68) | NMT2NMT1 | |
| SCHEMBL6870463 | 0.78 | NMT2 (0.44) | NMT2NMT1KDM4EMEN1LMNA | |
| SCHEMBL6863780 | 0.77 | NMT2 (0.64) | NMT2NMT1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6870237 | 0.74 | NMT2 (0.70) | NMT2NMT1KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | claimed |