SCHEMBL6868837

SCHEMBL6868837

O=S(=O)(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.O=c1ccc2c(S)cccc2o1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.37
CYP3A4 P08684 2/20 0.33
PGR P06401 1/20 0.32
HSD17B3 P37058 1/20 0.32
KCNA3 P22001 1/20 0.32
CA1 P00915 3/20 0.31
CA9 Q16790 3/20 0.31
CA2 P00918 2/20 0.31
CA5A P35218 2/20 0.31
CA12 O43570 2/20 0.31
LMNA P02545 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA7 P43166 1/20 0.30
MCL1 Q07820 1/20 0.30
SOST Q9BQB4 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA5B Q9Y2D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL6881212 0.87 CYP2A6 (0.42) CYP2A6CYP3A4PGRHSD17B3KCNA3
SCHEMBL5046429 0.76 CDC14B (0.32)
SCHEMBL6875856 0.76 GLA (0.44) CYP2A6CYP3A4CA1CA9CA2
SCHEMBL6878901 0.75 GAA (0.38) CYP3A4PGRHSD17B3CA1CA9
Hydrogen Sulfide SCHEMBL6868834 0.72 CYP2A6 (0.49) CYP2A6CYP3A4KCNA3CA1CA9
SCHEMBL6880971 0.72 CYP2A6 (0.41) CYP2A6CA1CA9CA12LMNA
SCHEMBL1593373 0.70 TRPA1 (0.34) CA1CA2
Benzenethiol SCHEMBL29745974 0.69 CA2 (0.39) CA1CA2
SCHEMBL15842333 0.67 CYP2A6 (0.50) CYP2A6CYP3A4PGRHSD17B3CA1
SCHEMBL1594212 0.66 TRPA1 (0.35) CYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed