Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466956 | 1.00 | MCHR1 (0.41) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6873584 | 0.88 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6873577 | 0.88 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6872857 | 0.87 | ACHE (0.43) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6463524 | 0.87 | ACHE (0.43) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6874596 | 0.86 | APLNR (0.44) | MCHR1ADRA2ANPY5RCNR1KCNH2 | |
| SCHEMBL6459873 | 0.86 | APLNR (0.44) | MCHR1ADRA2ANPY5RCNR1KCNH2 | |
| SCHEMBL6880445 | 0.85 | MCHR1 (0.43) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6880450 | 0.85 | MCHR1 (0.43) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6875669 | 0.85 | MCHR1 (0.41) | MCHR1ADRA2ANPY5RCNR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |