Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 11/20 | 0.51 |
| ▸ | F2 | P00734 | 6/20 | 0.51 |
| ▸ | F10 | P00742 | 3/20 | 0.51 |
| ▸ | KLK1 | P06870 | 1/20 | 0.51 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | F12 | P00748 | 2/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867628 | 0.92 | ADORA2A (0.60) | ADORA2AKLKB1F2F10KLK1 | |
| SCHEMBL6871169 | 0.88 | ADORA2A (0.54) | ADORA2AKLKB1F2KLK1HPGDS | |
| SCHEMBL6872074 | 0.83 | ADORA2A (0.56) | ADORA2AF2HPGDSF12 | |
| SCHEMBL6870348 | 0.83 | ADORA2A (0.56) | ADORA2AF12 | |
| SCHEMBL6871731 | 0.83 | ADORA2A (0.64) | ADORA2AKLKB1F2F10KLK1 | |
| SCHEMBL7114944 | 0.82 | ADORA2A (0.54) | ADORA2A | |
| SCHEMBL6873737 | 0.82 | L3MBTL1 (0.43) | ADORA2AL3MBTL1 | |
| SCHEMBL6870133 | 0.81 | ADORA2A (0.59) | ADORA2AKLKB1F2F12 | |
| SCHEMBL6869989 | 0.80 | ADORA2A (0.58) | ADORA2AKLKB1F2F12 | |
| SCHEMBL6871283 | 0.79 | PTGER2 (0.44) | ADORA2AKLKB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |