Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | MAP3K12 | Q12852 | 8/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869557 | 1.00 | PTK2 (0.40) | PTK2MAP3K12SOS1LRRK2TUBB4A | |
| SCHEMBL2060572 | 0.90 | PTK2 (0.42) | PTK2MAP3K12SOS1LRRK2ALDH1A1 | |
| SCHEMBL31525796 | 0.82 | PKM (0.40) | PTK2SOS1LRRK2ALDH1A1IDH1 | |
| SCHEMBL22652055 | 0.80 | SOS1 (0.43) | MAP3K12SOS1MTORPIK3CA | |
| SCHEMBL7045734 | 0.79 | PTK2 (0.36) | PTK2MAP3K12SOS1LRRK2IDH1 | |
| SCHEMBL6878299 | 0.79 | PTK2 (0.40) | PTK2SOS1LRRK2ALDH1A1IDH1 | |
| SCHEMBL6878306 | 0.79 | PTK2 (0.40) | PTK2SOS1LRRK2ALDH1A1IDH1 | |
| SCHEMBL7045737 | 0.79 | PTK2 (0.36) | PTK2MAP3K12SOS1LRRK2IDH1 | |
| SCHEMBL6878303 | 0.77 | IDH1 (0.37) | PTK2LRRK2IDH1KCNQ3KCNQ2 | |
| SCHEMBL30900450 | 0.76 | BRAF (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713499-B2 | ADENOSINE RECEPTOR AGONIST | HOFFMAN-LA ROCHE INC. | 2004-03-30 | — | — | US | disclosed |
| US-20030153566-A1 | 7-Amino-benzothiazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153566-A1 | 7-Amino-benzothiazole derivatives | ADORA1, ADORA2A, ADORA3 | PTK2 3126/4885MAP3K12 3754/4885SOS1 4160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.