Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878306 | 1.00 | PTK2 (0.40) | PTK2KCNQ3KCNQ2WNT3ASOS1 | |
| SCHEMBL6878057 | 0.83 | EPHX1 (0.51) | WNT3AALDH1A1POLBHTTGAA | |
| SCHEMBL7045734 | 0.83 | PTK2 (0.36) | PTK2KCNQ3KCNQ2SOS1LRRK2 | |
| SCHEMBL6869554 | 0.79 | PTK2 (0.40) | PTK2KCNQ3KCNQ2SOS1LRRK2 | |
| SCHEMBL6869557 | 0.79 | PTK2 (0.40) | PTK2KCNQ3KCNQ2SOS1LRRK2 | |
| SCHEMBL2060572 | 0.77 | PTK2 (0.42) | PTK2SOS1LRRK2IDH1ALDH1A1 | |
| SCHEMBL6878049 | 0.76 | ALDH1A1 (0.41) | PTK2KCNQ3KCNQ2WNT3ALRRK2 | |
| SCHEMBL6878303 | 0.74 | IDH1 (0.37) | PTK2KCNQ3KCNQ2LRRK2IDH1 | |
| SCHEMBL31525796 | 0.74 | PKM (0.40) | PTK2KCNQ3KCNQ2SOS1LRRK2 | |
| SCHEMBL3042603 | 0.71 | ALDH1A1 (0.54) | ALDH1A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713499-B2 | ADENOSINE RECEPTOR AGONIST | HOFFMAN-LA ROCHE INC. | 2004-03-30 | — | — | US | disclosed |
| US-20030153566-A1 | 7-Amino-benzothiazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153566-A1 | 7-Amino-benzothiazole derivatives | ADORA1, ADORA2A, ADORA3 | PTK2 3126/4885KCNQ3 850/4885KCNQ2 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.