Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867220 | 0.87 | MAPT (0.47) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL14519048 | 0.82 | HPGD (0.74) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL2831553 | 0.80 | MAPT (0.40) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL25232427 | 0.79 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL4949951 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4EHTTIMPDH2 | |
| SCHEMBL2830708 | 0.77 | HTT (0.52) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL3200271 | 0.76 | MAPT (0.38) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL7238315 | 0.76 | MAPT (0.43) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL2863488 | 0.76 | RORC (0.52) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL2829188 | 0.75 | MAPT (0.42) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812241-B2 | FOR PLANTS, HUMANS, VETERINARY MEDICINE | PFIZER INC. | 2004-11-02 | — | — | US | disclosed |
| US-20030130307-A1 | Heterocycles | BANKS BERNARD JOSEPH (GB) | 2003-07-10 | — | — | US | disclosed |
| US-6525079-B2 | Antiparasitic compounds such as 4-(2,2-dibromocyclopropyl)-1-(2,6-dichloro-4-trifluoromethylphenyl)-1,2,3 -triazole | PFIZER INC. | 2003-02-25 | — | — | US | disclosed |
| US-20010005725-A1 | Heterocycles | BANKS BERNARD JOSEPH (GB) | 2001-06-28 | — | — | US | disclosed |
| US-6110958-A | PARASITICIDES | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |
| US-6083965-A | ANTIPARASITIC AGENTS | PFIZER INC (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0957094-A1 | 1-(2-Halogenaryl)azoles as antiparasitic agents | PFIZER INC. (US) | 1999-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130307-A1 | Heterocycles | CYP1A1, CYP2E1, CYP1B1 | ALDH1A1 130/4885KDM4E 1844/4885HPGD 424/4885 |
| US-20010005725-A1 | Heterocycles | CYP1A1, CYP2E1, CYP1B1 | ALDH1A1 130/4885KDM4E 1844/4885HPGD 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.