Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869652 | 0.87 | ALDH1A1 (0.53) | MAPTHPGDALDH1A1NPSR1KDM4E | |
| SCHEMBL6865680 | 0.85 | CYP1A2 (0.36) | MAPTHPGDALDH1A1NPSR1KDM4E | |
| SCHEMBL2831553 | 0.80 | MAPT (0.40) | MAPTHPGDALDH1A1NPSR1KDM4E | |
| SCHEMBL7238315 | 0.76 | MAPT (0.43) | MAPTHPGDALDH1A1NPSR1KDM4E | |
| SCHEMBL3200271 | 0.76 | MAPT (0.38) | MAPTHPGDALDH1A1NPSR1KDM4E | |
| SCHEMBL2829188 | 0.75 | MAPT (0.42) | MAPTHPGDALDH1A1NPSR1KDM4E | |
| SCHEMBL3219619 | 0.75 | MAPT (0.40) | MAPTHPGDALDH1A1NPSR1KDM4E | |
| SCHEMBL3219634 | 0.74 | RECQL (0.39) | MAPTHPGDALDH1A1NPSR1KDM4E | |
| SCHEMBL2830708 | 0.74 | HTT (0.52) | MAPTHPGDALDH1A1NPSR1KDM4E | |
| SCHEMBL2863488 | 0.73 | RORC (0.52) | MAPTHPGDALDH1A1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812241-B2 | FOR PLANTS, HUMANS, VETERINARY MEDICINE | PFIZER INC. | 2004-11-02 | — | — | US | disclosed |
| US-20030130307-A1 | Heterocycles | BANKS BERNARD JOSEPH (GB) | 2003-07-10 | — | — | US | disclosed |
| US-6525079-B2 | Antiparasitic compounds such as 4-(2,2-dibromocyclopropyl)-1-(2,6-dichloro-4-trifluoromethylphenyl)-1,2,3 -triazole | PFIZER INC. | 2003-02-25 | — | — | US | disclosed |
| US-20010005725-A1 | Heterocycles | BANKS BERNARD JOSEPH (GB) | 2001-06-28 | — | — | US | disclosed |
| US-6110958-A | PARASITICIDES | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |
| US-6083965-A | ANTIPARASITIC AGENTS | PFIZER INC (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0957094-A1 | 1-(2-Halogenaryl)azoles as antiparasitic agents | PFIZER INC. (US) | 1999-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130307-A1 | Heterocycles | CYP1A1, CYP2E1, CYP1B1 | MAPT 4726/4885HPGD 424/4885ALDH1A1 130/4885 |
| US-20010005725-A1 | Heterocycles | CYP1A1, CYP2E1, CYP1B1 | MAPT 4726/4885HPGD 424/4885ALDH1A1 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.