Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TPH1 | P17752 | 4/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19112036 | 0.84 | PLK1 (0.49) | PLK1CA12CA1CA2CA9 | |
| SCHEMBL19112035 | 0.80 | PLK1 (0.51) | PLK1CA12CA1CA2CA9 | |
| SCHEMBL8252393 | 0.79 | S1PR1 (0.56) | PLK1CA12CA1CA2CA9 | |
| SCHEMBL856937 | 0.79 | PLK1 (0.55) | PLK1CA12CA1CA2CA9 | |
| SCHEMBL14210018 | 0.77 | PLK1 (0.55) | PLK1CA12CA1CA2CA9 | |
| SCHEMBL9971549 | 0.76 | S1PR1 (0.54) | PLK1CA12CA1CA2CA9 | |
| SCHEMBL13415301 | 0.74 | L3MBTL1 (0.69) | PLK1CA12CA1CA2CA9 | |
| SCHEMBL31524131 | 0.74 | TPH1 (0.67) | PLK1LMNATSHRNFKB1RAB9A | |
| SCHEMBL8436680 | 0.74 | MAPT (0.61) | PLK1CA12CA1CA2CA9 | |
| SCHEMBL5316004 | 0.73 | CA12 (0.48) | PLK1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023864-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2011-03-03 | — | — | WO | disclosed |