Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069902 | 0.86 | EPAS1 (0.56) | EPAS1ALDH1A1ESPL1SLC22A12 | |
| SCHEMBL31729379 | 0.79 | TRPV4 (0.48) | EPAS1TRPV4CYP11B1CYP11B2SLC22A12 | |
| SCHEMBL23579849 | 0.79 | CA2 (0.56) | ALDH1A1TRPV4CA1CA2 | |
| SCHEMBL1156122 | 0.79 | TRPV4 (0.48) | EPAS1TRPV4CYP11B1CYP11B2SLC22A12 | |
| SCHEMBL2888292 | 0.79 | EPAS1 (0.51) | EPAS1TRPV4CYP11B1CYP11B2SLC22A12 | |
| SCHEMBL2789258 | 0.78 | ALDH1A1 (0.64) | EPAS1ALDH1A1ESPL1CA1CA2 | |
| SCHEMBL3299113 | 0.73 | SLC22A12 (0.45) | EPAS1TRPV4SLC22A12 | |
| SCHEMBL2789621 | 0.73 | EPAS1 (0.46) | EPAS1ALDH1A1 | |
| SCHEMBL29217918 | 0.73 | ALDH1A1 (0.52) | EPAS1ALDH1A1ESPL1 | |
| SCHEMBL2325842 | 0.72 | CA1 (0.50) | EPAS1ALDH1A1TRPV4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6805920-B2 | For producing liquid crystal display (LCD) | NITTO DENKO CORPORATION (JP) | 2004-10-19 | — | — | US | disclosed |
| US-20030072893-A1 | Polymerizable liquid crystal compound and optical film | NITTO DENKO CORPORATION (JP) | 2003-04-17 | — | — | US | disclosed |
| EP-0354434-A2 | Process for the preparation of rod-like compounds | MERCK PATENT GmbH (DE) | 1990-02-14 | — | — | EP | disclosed |