Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044854 | 0.97 | HPGD (0.32) | HPGDSMN1; SMN2PDE10ALMNAALPG | |
| SCHEMBL6861630 | 0.95 | PDE10A (0.32) | HPGDSMN1; SMN2PDE10ALMNAALPG | |
| SCHEMBL6871021 | 0.92 | PDE10A (0.30) | PDE10ALMNAALPGHTT | |
| SCHEMBL6865786 | 0.87 | NMT2 (0.36) | HPGDPDE10A | |
| SCHEMBL6866405 | 0.85 | PDE10A (0.31) | PDE10ALMNAALPGHTT | |
| SCHEMBL6865553 | 0.85 | PDE10A (0.31) | PDE10ALMNAALPGHTT | |
| SCHEMBL6869856 | 0.83 | — | — | |
| SCHEMBL6861471 | 0.83 | ALDH1A1 (0.32) | HPGDPDE10ALMNA | |
| SCHEMBL6866232 | 0.83 | KCNH2 (0.38) | PDE10ALMNAHTT | |
| SCHEMBL6861534 | 0.83 | PDE10A (0.30) | PDE10ALMNAALPGHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091957-B1 | PYRIMIDIN-AMINOMETHYL-PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE CONTROL OF HELICOBACTER BACTERIA | ALTANA PHARMA AG (DE) | 2004-12-15 | — | — | EP | disclosed |
| US-6395732-B1 | BACTERICIDES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2002-05-28 | — | — | US | disclosed |