Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 8/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020390 | 0.80 | PNMT (0.37) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL1275883 | 0.80 | PNMT (0.58) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL456019 | 0.80 | PNMT (0.62) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL1703196 | 0.78 | PNMT (0.55) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL30606684 | 0.77 | PNMT (0.68) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL633763 | 0.77 | PNMT (0.68) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL3979804 | 0.76 | PNMT (0.67) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7538016 | 0.76 | PNMT (0.62) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL28344069 | 0.76 | PNMT (0.62) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL9610281 | 0.76 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6822109-B2 | TRIHYDROCARBYLSILYLATION; ADDITION POLYMERIZATION OF OLEFINS | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2004-11-23 | — | — | US | disclosed |