Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.36 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870360 | 0.69 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL11613569 | 0.60 | KMT2A (0.48) | — | |
| SCHEMBL17206979 | 0.58 | GAA (0.51) | — | |
| SCHEMBL13879413 | 0.58 | MGLL (0.41) | ADCY2 | |
| SCHEMBL29763773 | 0.55 | CYP1A2 (0.57) | — | |
| SCHEMBL11724977 | 0.54 | MEN1 (0.41) | — | |
| SCHEMBL8664646 | 0.54 | ALDH1A1 (0.41) | — | |
| SCHEMBL5952375 | 0.54 | METAP1 (0.41) | — | |
| SCHEMBL3422032 | 0.53 | MEN1 (0.48) | MAPK14 | |
| SCHEMBL12670455 | 0.53 | PTPRC (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809199-B2 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES | MERCK & CO., INC. | 2004-10-26 | — | — | US | disclosed |