Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15080038 | 0.87 | CYP1A2 (0.49) | TAAR1SIRT2FFAR1FFAR4IDO1 | |
| SCHEMBL1259945 | 0.79 | PARP10 (0.62) | KCNA3TAAR1ALDH1A1FFAR1FFAR4 | |
| SCHEMBL14328006 | 0.79 | DRD2 (0.52) | ALDH1A1DRD2DRD4DRD3GAA | |
| SCHEMBL9331124 | 0.79 | TAAR1 (0.58) | TAAR1SIRT2ALDH1A1FFAR1FFAR4 | |
| SCHEMBL9854724 | 0.76 | KCNA3 (0.52) | KCNA3TAAR1ALDH1A1RECQLIDO1 | |
| SCHEMBL11705264 | 0.76 | HRH1 (0.56) | KCNA3TAAR1ALDH1A1RECQLFFAR1 | |
| SCHEMBL18919802 | 0.76 | KCNA3 (0.52) | KCNA3TAAR1ALDH1A1RECQLNPC1 | |
| SCHEMBL12687834 | 0.76 | HDAC6 (0.59) | SIRT2ALDH1A1FFAR1FFAR4PARP10 | |
| SCHEMBL28451246 | 0.75 | TAAR1 (0.54) | TAAR1SIRT2ALDH1A1FFAR1FFAR4 | |
| SCHEMBL31245544 | 0.75 | TAAR1 (0.54) | TAAR1SIRT2ALDH1A1IDO1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806283-B2 | SUCH AS SPIRO(9,10-DIHYDROANTHRACENE)-9,3'-PYRROLIDINE; FOR USE AS ANTIDEPRESSANT AND ANTIANXIETY AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2004-10-19 | — | — | US | disclosed |
| US-20030232872-A1 | Selective serotonin receptor antagonists and therapeutic applications thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232872-A1 | Selective serotonin receptor antagonists and therapeutic applications thereof | HTR2A, HTR7, HTR1A | KCNA3 2697/4885TAAR1 87/4885SIRT2 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.