Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 9/20 | 0.44 |
| ▸ | NMT1 | P30419 | 9/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3474351 | 0.86 | NMT2 (0.61) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL6870343 | 0.79 | NMT2 (0.46) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL6870905 | 0.78 | MAOB (0.49) | NMT2NMT1MEN1KMT2ALMNA | |
| SCHEMBL6863415 | 0.77 | NMT2 (0.72) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL6870237 | 0.76 | NMT2 (0.70) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL6869324 | 0.75 | NMT2 (0.49) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL6868394 | 0.74 | NMT2 (0.71) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL6868285 | 0.74 | NMT2 (0.72) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL6870953 | 0.73 | NMT2 (0.52) | NMT2NMT1 | |
| SCHEMBL6864133 | 0.71 | NMT2 (0.59) | NMT2NMT1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | claimed |