Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869236 | 0.88 | USP2 (0.38) | ADORA2APDE11AALDH1A1LMNAMEN1 | |
| SCHEMBL6869933 | 0.86 | ADORA2A (0.41) | ADORA2APDE11ALMNAMEN1KMT2A | |
| SCHEMBL6863049 | 0.85 | ADORA2A (0.45) | ADORA2APDE11AALDH1A1NPSR1KDM4E | |
| SCHEMBL6873153 | 0.84 | ADORA2A (0.38) | ADORA2APDE11AHPGDABL1BCR | |
| SCHEMBL6867998 | 0.84 | ADORA2A (0.52) | ADORA2AALDH1A1NPSR1KDM4ELMNA | |
| SCHEMBL6871963 | 0.83 | ADORA2A (0.35) | ADORA2APDE11AABL1BCR | |
| SCHEMBL6870657 | 0.82 | ADORA2A (0.50) | ADORA2APDE11AALDH1A1NPSR1KDM4E | |
| SCHEMBL6869532 | 0.81 | ADORA2A (0.36) | ADORA2APDE11A | |
| SCHEMBL6874251 | 0.80 | ADORA2A (0.43) | ADORA2APDE11AHPGD | |
| SCHEMBL6872068 | 0.80 | ADORA2A (0.52) | ADORA2APDE11AALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | claimed |