SCHEMBL687062

SCHEMBL687062

CCCCN[SiH](CCC)OC

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ADH1B P00325 1/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30
ADH7 P40394 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31473071 0.85 DNM1 (0.31) TSHRCA12CA1CA2CA7
SCHEMBL4312581 0.80
SCHEMBL27859686 0.77 DNM1 (0.31) TSHR
SCHEMBL5664587 0.77 TSHR (0.30) TSHR
SCHEMBL27859876 0.74 DNM1 (0.38) TSHR
SCHEMBL16396823 0.73 TSHR (0.38) TSHRADH1BADH1CADH1AADH7
SCHEMBL5044831 0.70
SCHEMBL17373593 0.68 ACHE (0.31) TSHR
SCHEMBL27999229 0.68 TSHR (0.46) TSHRADH1BADH1CADH1AADH7
SCHEMBL3389390 0.66 TSHR (0.45) TSHRADH1BADH1CADH1AADH7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829925-B1 RUBBER COMPOSITION, METHOD FOR PRODUCING SAME AND TIRE BRIDGESTONE CORP (JP) 2012-02-29 EP disclosed
US-20090124742-A1 Rubber Composition, Method for Producing Same and Tire BRIDGESTONE CORPORATION (JP) 2009-05-14 US disclosed
EP-1829925-A1 RUBBER COMPOSITION, METHOD FOR PRODUCING SAME AND TIRE Bridgestone Corporation (JP) 2007-09-05 EP disclosed