Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | NSD2 | O96028 | 3/20 | 0.47 |
| ▸ | MMP14 | P50281 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 2/20 | 0.47 |
| ▸ | MPL | P40238 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | ATIC | P31939 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870626 | 1.00 | MEN1 (0.61) | MEN1KMT2AKDM4ENPC1LMNA | |
| SCHEMBL3790419 | 0.90 | CYP1A2 (0.50) | MEN1KMT2AKDM4ENPC1LMNA | |
| SCHEMBL31661136 | 0.81 | CYP1A2 (0.60) | MEN1KMT2ALMNACYP1A2NSD2 | |
| SCHEMBL408152 | 0.81 | POLB (0.58) | MEN1KMT2ANPC1MAPTCYP1A2 | |
| SCHEMBL31158053 | 0.81 | POLB (0.58) | MEN1KMT2ANPC1MAPTCYP1A2 | |
| SCHEMBL408151 | 0.81 | POLB (0.58) | MEN1KMT2ANPC1MAPTCYP1A2 | |
| SCHEMBL11144896 | 0.80 | IDE (0.54) | MEN1KMT2ANPC1MAPTCYP1A2 | |
| SCHEMBL11144901 | 0.80 | IDE (0.54) | MEN1KMT2ANPC1MAPTCYP1A2 | |
| SCHEMBL7205854 | 0.80 | SUMO2 (0.43) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL8744500 | 0.80 | SUMO2 (0.43) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6808616-B2 | LOW TEMPERATURE, DIRECT ELECTROCHEMICAL REDUCTION OF A SULFOPHENYLAZOPHENOL DERIVATIVE WITH CARBON ELECTRODE | NOVEON IP HOLDINGS CORP. | 2004-10-26 | — | — | US | disclosed |
| US-20030098243-A1 | Process for the preparation of 5-aminosalicyclic acid | NOVEON, INC. | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030098243-A1 | Process for the preparation of 5-aminosalicyclic acid | PGA5, AASDHPPT, TPMT | MEN1 4714/4885KMT2A 3349/4885KDM4E 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.