Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870329 | 0.89 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6870605 | 0.84 | ADORA2A (0.58) | ADORA2A | |
| SCHEMBL6870096 | 0.83 | ADORA2A (0.60) | ADORA2A | |
| SCHEMBL6871448 | 0.82 | ADORA2A (0.65) | ADORA2A | |
| SCHEMBL6871192 | 0.82 | ADORA2A (0.58) | ADORA2ASMN1; SMN2 | |
| SCHEMBL6871992 | 0.82 | ADORA2A (0.58) | ADORA2ASMN1; SMN2 | |
| SCHEMBL6866973 | 0.81 | BACE1 (0.48) | SMN1; SMN2 | |
| SCHEMBL6871906 | 0.81 | ADORA2A (0.46) | ADORA2A | |
| SCHEMBL6871700 | 0.81 | SMN1; SMN2 (0.41) | ADORA2ASMN1; SMN2 | |
| SCHEMBL6873028 | 0.81 | ADORA2A (0.73) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |