Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863403 | 0.91 | ADORA2A (0.36) | HSF1 | |
| SCHEMBL6872431 | 0.85 | HDAC3 (0.40) | ALDH1A1HSF1 | |
| SCHEMBL6863200 | 0.83 | ADORA2A (0.38) | HSF1 | |
| SCHEMBL6873153 | 0.81 | ADORA2A (0.38) | HSF1 | |
| SCHEMBL6869933 | 0.81 | ADORA2A (0.41) | HSF1 | |
| SCHEMBL6874251 | 0.80 | ADORA2A (0.43) | BCHEHSF1 | |
| SCHEMBL6869532 | 0.80 | ADORA2A (0.36) | BCHEHSF1 | |
| SCHEMBL6870178 | 0.78 | ADORA2A (0.50) | ALDH1A1HSD17B10 | |
| SCHEMBL6871963 | 0.77 | ADORA2A (0.35) | — | |
| SCHEMBL6871432 | 0.76 | ADORA2A (0.40) | ALDH1A1HSF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | claimed |