Sulfuric Acid

Sulfuric Acid

SCHEMBL687086

Cc1cc(F)c(N)cc1N.O.O=S(=O)(O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.39
TSHR P16473 3/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 7/20 0.38
HSD17B10 Q99714 3/20 0.38
CYP1A2 P05177 2/20 0.38
ALOX15 P16050 2/20 0.38
CASP7 P55210 1/20 0.38
HIF1A Q16665 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
CA12 O43570 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
MAPT P10636 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL4825164 1.00 CYP3A4 (0.39) CYP3A4TSHRMAPK1ALDH1A1HSD17B10
Sulfuric Acid SCHEMBL29509683 0.98 CYP3A4 (0.41) CYP3A4TSHRMAPK1ALDH1A1HSD17B10
Sulfuric Acid SCHEMBL2917314 0.98 CYP3A4 (0.41) CYP3A4TSHRMAPK1ALDH1A1HSD17B10
SCHEMBL457125 0.85 CYP3A4 (0.52) CYP3A4TSHRMAPK1ALDH1A1HSD17B10
SCHEMBL29358157 0.85 CYP3A4 (0.52) CYP3A4TSHRMAPK1ALDH1A1HSD17B10
Sulfuric Acid SCHEMBL8642578 0.83 CA1 (0.45) CYP3A4TSHRALDH1A1HSD17B10ALOX15
Sulfuric Acid SCHEMBL2984729 0.82 BRD4 (0.45) CYP3A4TSHRMAPK1ALDH1A1HSD17B10
Sulfuric Acid SCHEMBL28705973 0.81 CYP3A4 (0.55) CYP3A4TSHRMAPK1ALDH1A1HSD17B10
Sulfuric Acid SCHEMBL8639611 0.80 CYP3A4 (0.60) CYP3A4TSHRMAPK1ALDH1A1HSD17B10
Sulfuric Acid SCHEMBL23804110 0.76 CA1 (0.43) CYP3A4TSHRALDH1A1HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7226487-B2 Oxidative dyeing keratin fibers THE PROCTER & GAMBLE COMPANY (US) 2007-06-05 US claimed
EP-1646606-A1 2-(AMINO OR SUBSTITUTED AMINO)-5-(SUBSTITUTED OXYMETHYL)-PHENOL COMPOUNDS, DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2006-04-19 EP claimed
WO-2005007615-A1 2-(AMINO OR SUBSTITUTED AMINO)-5-(SUBSTITUTED OXYMETHYL)-PHENOL COMPOUNDS, DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-01-27 WO claimed
US-20050005370-A1 2-(Amino or substituted amino)-5-(substituted oxymethyl)-phenol compounds, dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY 2005-01-13 US claimed
US-12018232-B2 Multilayer dissolvable solid article containing solid particles for making the same THE PROCTER & GAMBLE COMPANY (US) 2024-06-25 US disclosed
CN-114867447-A Multilayer dissolvable solid article comprising solid particles for making multilayer dissolvable solid article 宝洁公司 2022-08-05 CN disclosed
US-20220160614-A1 HAIR COLORANT COMPOSITIONS WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2022-05-26 US disclosed
EP-3941424-A1 HAIR COLORANT COMPOSITIONS Wella International Operations Switzerland Sàrl (CH) 2022-01-26 EP disclosed
WO-2020188001-A1 HAIR COLORANT COMPOSITIONS HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-09-24 WO disclosed
EP-1832273-B1 Thickened hair colourant and bleaching compositions NOXELL CORP (US) 2020-02-26 EP disclosed
EP-2760425-B1 FOAM OXIDATIVE HAIR COLORANT COMPOSITION WITH THE FREE-BASE OF 1, 4-DIAMINO-2-METHOXMETHYL BENZENE NOXELL CORP (US) 2019-07-31 EP disclosed
EP-1642563-B1 Method of rapid hair dyeing NOXELL CORP (US) 2019-06-26 EP disclosed
EP-1037593-B1 AGENT AND METHOD FOR DYEING FIBRES WELLA AG (DE) 2004-02-04 EP disclosed
EP-0891971-B1 Bispyrazole-aza compounds, processes for their preparation, and hair dyeing agents containing these compounds WELLA AG (DE) 2003-11-12 EP disclosed
US-6379400-B1 DYEING FIBERS, SOLVENT OF WATER OR ALCOHOL AND NITROANILINE DYE WELLA AKTIENGESELLSCHAFT (DE) 2002-04-30 US disclosed
EP-0863739-B1 HAIR DYE WELLA AG (DE) 2002-04-17 EP disclosed
EP-1037593-A1 AGENT AND METHOD FOR DYEING FIBRES Wella Aktiengesellschaft (DE) 2000-09-27 EP disclosed
WO-2000021496-A1 AGENT AND METHOD FOR DYEING FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2000-04-20 WO disclosed
US-5865855-A COUPLING TWO PYRAZOLE COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 1999-02-02 US disclosed
EP-0891971-A1 Bispyrazole-aza compounds, processes for their preparation, and hair dyeing agents containing these compounds Wella Aktiengesellschaft (DE) 1999-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050005370-A1 2-(Amino or substituted amino)-5-(substituted oxymethyl)-phenol compounds, dyeing compositions containing them, and use thereof KRT18, LOX, TYR CYP3A4 973/4885TSHR 4833/4885MAPK1 996/4885
US-20220160614-A1 HAIR COLORANT COMPOSITIONS LPO, SHH, ALDH1A3 CYP3A4 2305/4885TSHR 2996/4885MAPK1 2014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.