Sugi Predict

Sugi Predict / Compounds / SCHEMBL6870910

SCHEMBL6870910

SCHEMBL6870910

CC(C)(C)c1cc(N=Nc2ccc(Cl)cc2[N+](=O)[O-])c(O)c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.40
▸ KMT2A Q03164 6/20 0.40
▸ HTT P42858 4/20 0.40
▸ GALR3 O60755 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ PSEN1 P49768 1/20 0.38
▸ PSEN2 P49810 1/20 0.38
▸ APH1B Q8WW43 1/20 0.38
▸ NCSTN Q92542 1/20 0.38
▸ APH1A Q96BI3 1/20 0.38
▸ PSENEN Q9NZ42 1/20 0.38
▸ GPR35 Q9HC97 1/20 0.38
▸ LMNA P02545 4/20 0.37
▸ POLB P06746 1/20 0.37
▸ MAPT P10636 5/20 0.37
▸ MAPK1 P28482 4/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ GAA P10253 2/20 0.37
▸ KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30200323 1.00 MEN1 (0.40) MEN1KMT2AHTTGALR3SMN1; SMN2
SCHEMBL6870907 1.00 MEN1 (0.40) MEN1KMT2AHTTGALR3SMN1; SMN2
SCHEMBL30200284 1.00 MEN1 (0.40) MEN1KMT2AHTTGALR3SMN1; SMN2
SCHEMBL9327604 0.91 KMT2A (0.40) MEN1KMT2AHTTGALR3SMN1; SMN2
SCHEMBL9866027 0.91 KMT2A (0.40) MEN1KMT2AHTTGALR3SMN1; SMN2
SCHEMBL7524143 0.89 KIF18A (0.40) MEN1KMT2AHTTL3MBTL1PSEN1
SCHEMBL7524148 0.89 KIF18A (0.40) MEN1KMT2AHTTL3MBTL1PSEN1
SCHEMBL29603532 0.88 MEN1 (0.41) MEN1KMT2AHTTGALR3SMN1; SMN2
SCHEMBL7759721 0.88 MEN1 (0.41) MEN1KMT2AHTTGALR3SMN1; SMN2
SCHEMBL7759727 0.88 MEN1 (0.41) MEN1KMT2AHTTGALR3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3978074-A CATALYTIC HYDROGENATION UNIROYAL INC. (US) 1976-08-31 — — US claimed
CN-115608398-A M-N-C catalyst and application thereof in synthesis of benzotriazole compounds 天津大学 2023-01-17 — — CN disclosed
US-6815550-B2 DIAZOTIZING A 5-PERFLUOROALKYL-O-NITROANILINE WITH SULFURIC ACID AND ALKALI METAL NITRITE OR NITROSYLSULFURIC ACID; COUPLING WITH A PHENOL; AND REDUCING THE MONOAZOBENZENE INTERMEDIATE TO THE CORRESPONDING 2H-BENZOTRIAZOLE CIBA SPECIALTY CHEMICALS CORPORATION 2004-11-09 — — US disclosed
US-6605727-B2 Processes for the preparation of benzotriazole UV absorbers CIBA SPECIALTY CHEMICALS CORPORATION 2003-08-12 — — US disclosed
US-20030130524-A1 Processes for the preparation of benzotriazole UV absorbers WOOD MERVIN G (US) 2003-07-10 — — US disclosed
US-20030120083-A1 Processes for the preparation of benzotriazole UV absorbers WOOD MERVIN G (US) 2003-06-26 — — US disclosed
US-6566507-B2 Processes for the preparation of benzotriazole UV absorbers CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-20 — — US disclosed
EP-1305298-A2 PROCESSES FOR THE PREPARATION OF BENZOTRIAZOLE UV ABSORBERS Ciba SC Holding AG (CH) 2003-05-02 — — EP disclosed
US-20020035175-A1 Processes for the preparation of benzotriazole UV absorbers CIBA SPECIALTY CHEMICALS CORP. 2002-03-21 — — US disclosed
WO-2002012202-A2 PROCESSES FOR THE PREPARATION OF BENZOTRIAZOLE UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDINGS INC. (CH) 2002-02-14 — — WO disclosed
US-5104992-A METHOD OF PREPARING 2-PHENYL BENEZOTHRIAZOLES CHEMIPRO KASEI KAISHA, LTD. (JP) 1992-04-14 — — US disclosed
EP-0380840-A1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-08-08 — — EP disclosed
EP-0380839-A1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-08-08 — — EP disclosed
US-4943637-A Method for preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-07-24 — — US disclosed
EP-0160246-B1 A METHOD FOR PRODUCING A 2-PHENYLBENZOTRIAZOLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-01-24 — — EP disclosed
US-4835284-A Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1989-05-30 — — US disclosed
EP-0263905-A1 Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1988-04-20 — — EP disclosed
EP-0160246-A1 A method for producing A 2-phenylbenzotriazole SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-11-06 — — EP disclosed
US-4220788-A Process for the preparation of 2-aryl-2H-benzotriazoles CIBA-GEIGY CORPORATION (US) 1980-09-02 — — US disclosed
US-4001266-A PROCESS FOR THE MANUFACTURE OF 2-(2-HYDROXYPHENYL)BENZTRIAZOLES CIBA-GEIGY CORPORATION (US) 1977-01-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035175-A1 Processes for the preparation of benzotriazole UV absorbers SULT1A1, SULT2A1, NISCH MEN1 2743/4885KMT2A 609/4885HTT 664/4885
US-20030120083-A1 Processes for the preparation of benzotriazole UV absorbers SULT1A1, SULT2A1, NISCH MEN1 2743/4885KMT2A 609/4885HTT 664/4885
US-20030130524-A1 Processes for the preparation of benzotriazole UV absorbers SULT1A1, SULT2A1, NISCH MEN1 2743/4885KMT2A 609/4885HTT 664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.