Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 6/20 | 0.61 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.53 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779928 | 0.82 | HRH2 (0.54) | HRH2SLC5A1SLC5A2HTR2AHTR2C | |
| SCHEMBL6872329 | 0.79 | DRD2 (0.50) | HRH2SLC5A1SLC5A2HTR2AHTR2C | |
| SCHEMBL6780420 | 0.78 | DRD2 (0.59) | HRH2SLC5A1SLC5A2HTR2AHTR2C | |
| SCHEMBL27494197 | 0.77 | ALDH1A1 (0.59) | HRH2SLC5A1SLC5A2DRD2HTR6 | |
| SCHEMBL5341713 | 0.77 | HRH2 (0.73) | HRH2HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL5340949 | 0.76 | HRH2 (1.00) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6777121 | 0.76 | DRD2 (0.62) | HRH2SLC5A1SLC5A2HTR2AHTR2C | |
| SCHEMBL5355591 | 0.76 | HRH2 (0.56) | HRH2SLC5A1SLC5A2HTR2AHTR2C | |
| SCHEMBL27493414 | 0.76 | SLC5A1 (0.56) | SLC5A1SLC5A2DRD2HTR6CNR2 | |
| SCHEMBL27581380 | 0.76 | HRH2 (0.58) | HRH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183251-B1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA SA (ES) | 2004-02-11 | — | — | EP | disclosed |