Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | JAK3 | P52333 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15114905 | 0.81 | KCNH2 (0.56) | MAOAMAOBJAK2JAK3KDM4E | |
| SCHEMBL3951624 | 0.81 | KDM4E (0.52) | MAOAMAOBJAK2JAK3KDM4E | |
| SCHEMBL10005387 | 0.79 | CYP2D6 (0.56) | JAK2JAK3KDM4EHPGDHSD17B10 | |
| SCHEMBL28616686 | 0.78 | KDM4E (0.48) | MAOAMAOBJAK2JAK3KDM4E | |
| SCHEMBL30487250 | 0.76 | CXCR4 (0.68) | MAOAMAOBKDM4ENPC1RAB9A | |
| SCHEMBL229311 | 0.76 | CXCR4 (0.68) | MAOAMAOBKDM4ENPC1RAB9A | |
| SCHEMBL5478136 | 0.74 | KCNH2 (0.49) | MAOAMAOBJAK2JAK3KDM4E | |
| SCHEMBL20837976 | 0.73 | MAOA (1.00) | MAOAMAOBKDM4ENPC1RAB9A | |
| SCHEMBL6754285 | 0.73 | MAOA (0.64) | MAOAMAOBKDM4ENPC1RAB9A | |
| SCHEMBL15830499 | 0.73 | NOS2 (0.67) | MAOAMAOBKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091957-B1 | PYRIMIDIN-AMINOMETHYL-PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE CONTROL OF HELICOBACTER BACTERIA | ALTANA PHARMA AG (DE) | 2004-12-15 | — | — | EP | disclosed |