Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266418 | 0.71 | RAB9A (0.54) | MAPTTSHRHSD17B10SMN1; SMN2HPGD | |
| SCHEMBL9369418 | 0.68 | MEN1 (0.47) | MAPTTSHRHSD17B10SMN1; SMN2HPGD | |
| SCHEMBL15987441 | 0.65 | RAB9A (0.66) | MAPTTSHRHSD17B10SMN1; SMN2HPGD | |
| SCHEMBL17544480 | 0.64 | CYP1A2 (0.43) | MAPTTSHRHSD17B10SMN1; SMN2HPGD | |
| SCHEMBL448303 | 0.62 | HTT (0.50) | MAPTTSHRHSD17B10HPGDKDM4E | |
| SCHEMBL18346214 | 0.61 | TAAR1 (0.43) | MAPTHSD17B10SMN1; SMN2HPGDCYP2C19 | |
| SCHEMBL10646248 | 0.61 | HTT (0.48) | MAPTTSHRHSD17B10SMN1; SMN2HPGD | |
| SCHEMBL7654044 | 0.61 | HTT (0.68) | MAPTTSHRHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL91161 | 0.60 | — | — | |
| SCHEMBL7050984 | 0.60 | HTT (0.72) | MAPTTSHRHSD17B10SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1388535-A1 | Acylated arylcycloalkylamines and their use as pharmaceuticals | Aventis Pharma Deutschland GmbH (DE) | 2004-02-11 | — | — | EP | disclosed |