Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.56 |
| ▸ | MAX | P61244 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | UBE2I | P63279 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869924 | 0.85 | CHRM4 (0.47) | MYCMAXKMT2AADORA2AMEN1 | |
| SCHEMBL6871169 | 0.82 | ADORA2A (0.54) | LMNASMN1; SMN2KMT2AADORA2AMEN1 | |
| SCHEMBL6870639 | 0.82 | ADORA2A (0.59) | SMN1; SMN2ADORA2AALDH1A1UBE2ISAE1 | |
| SCHEMBL6870583 | 0.80 | ADORA2A (0.66) | SMN1; SMN2KMT2AADORA2AMEN1ALDH1A1 | |
| SCHEMBL6870384 | 0.80 | ADORA2A (0.58) | LMNASMN1; SMN2ADORA2AALDH1A1KDM4E | |
| SCHEMBL6873589 | 0.80 | ADORA2A (0.56) | LMNASMN1; SMN2KMT2AADORA2AMEN1 | |
| SCHEMBL6873046 | 0.80 | ADORA2A (0.56) | LMNASMN1; SMN2KMT2AADORA2AALDH1A1 | |
| SCHEMBL6871254 | 0.80 | ADORA2A (0.56) | LMNASMN1; SMN2KMT2AADORA2AALDH1A1 | |
| SCHEMBL6873334 | 0.79 | ADORA2A (0.58) | ADORA2AALDH1A1HPGDCHRM4NPC1 | |
| SCHEMBL6863086 | 0.79 | PLAU (0.44) | LMNASMN1; SMN2ADORA2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |