Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863351 | 0.89 | PLAU (0.47) | PLAUCYP2C19CYP2D6CHRM4HPGD | |
| SCHEMBL6871570 | 0.88 | HPGD (0.46) | CYP2C19HPGDKDM4EALDH1A1LMNA | |
| SCHEMBL6869899 | 0.88 | SLC16A3 (0.43) | CYP2C19CYP2D6CHRM4HPGDKDM4E | |
| SCHEMBL6871193 | 0.88 | KMT2A (0.41) | CYP2D6KDM4EALDH1A1LMNAADORA2A | |
| SCHEMBL6869624 | 0.86 | ADORA2A (0.41) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL6873034 | 0.86 | ADORA2A (0.39) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL6867527 | 0.84 | ADORA2A (0.38) | HPGDKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6870566 | 0.83 | ADORA2A (0.45) | CYP2D6HPGDKDM4EALDH1A1LMNA | |
| SCHEMBL6863519 | 0.83 | ADORA2A (0.44) | HPGDKDM4EALDH1A1SMN1; SMN2ADORA2A | |
| SCHEMBL6863144 | 0.83 | NAAA (0.39) | L3MBTL1ADORA2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |