Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | MAX | P61244 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870516 | 0.90 | KDM4E (0.46) | ALDH1A1KMT2AGAADHFRKDM4E | |
| SCHEMBL6867467 | 0.88 | KDM4E (0.46) | ALDH1A1HPGDCYP2C9KMT2ACYP1A2 | |
| SCHEMBL6873737 | 0.88 | L3MBTL1 (0.43) | TP53ALDH1A1HPGDKMT2AHDAC1 | |
| SCHEMBL6870625 | 0.87 | MAPK10 (0.45) | TP53ALDH1A1CYP2C19GAAKDM4E | |
| SCHEMBL6872088 | 0.85 | MYC (0.56) | CHRM4MYCMAXALDH1A1HPGD | |
| SCHEMBL6863441 | 0.84 | HPGD (0.45) | TP53ALDH1A1HPGDKMT2ACYP1A2 | |
| SCHEMBL6871169 | 0.83 | ADORA2A (0.54) | CHRM4KMT2AKDM1AHDAC1HDAC2 | |
| SCHEMBL6871432 | 0.83 | ADORA2A (0.40) | TP53ALDH1A1HPGDKMT2AHDAC2 | |
| SCHEMBL6867623 | 0.80 | F2 (0.43) | ALDH1A1HPGDKMT2AHDAC1HDAC6 | |
| SCHEMBL6872077 | 0.80 | ADORA2A (0.42) | ALDH1A1HPGDKMT2ADHFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |