SCHEMBL6872095

SCHEMBL6872095

CCN(CC)c1ccc(Nc2ccccc2F)c2c1C(=O)OC21c2ccccc2Oc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
ALDH1A1 P00352 3/20 0.32
CYP2C9 P11712 2/20 0.32
HPGD P15428 2/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
BRCA1 P38398 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
EGFR P00533 1/20 0.30
CXCL8 P10145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4379777 0.88 CYP3A4 (0.35) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL6652999 0.86 ALDH1A1 (0.35) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL9855220 0.85 ALDH1A1 (0.33) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL9442975 0.85 CYP3A4 (0.37) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL10591631 0.84 ALOX5 (0.40) CYP3A4ALDH1A1ALOX15HSD17B10SMN1; SMN2
SCHEMBL6882234 0.84 HPGD (0.34) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL10387584 0.84 EGFR (0.41) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL2841971 0.82 CYP3A4 (0.41) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL10447181 0.81 PGR (0.38) CYP3A4ALDH1A1CYP2C9HPGDALOX15
SCHEMBL10596233 0.79 EGFR (0.35) CYP3A4ALDH1A1HPGDSMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-0424914-A2 Recording material NEW OJI PAPER CO., LTD. (JP) 1991-05-02 EP disclosed
EP-0403833-A2 Recording material NEW OJI PAPER CO., LTD. (JP) 1990-12-27 EP disclosed