Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.59 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.59 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.59 |
| ▸ | STS | P08842 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665713 | 0.87 | MEN1 (0.70) | KMT2AMEN1ENPP2ENPP1ENPP3 | |
| SCHEMBL29613371 | 0.87 | ENPP2 (0.63) | KMT2AMEN1ENPP2ENPP1ENPP3 | |
| SCHEMBL18179825 | 0.86 | MEN1 (0.60) | KMT2AMEN1ENPP2ENPP1ENPP3 | |
| SCHEMBL4126086 | 0.86 | MEN1 (0.60) | KMT2AMEN1ENPP2ENPP1ENPP3 | |
| SCHEMBL9852204 | 0.86 | MEN1 (0.60) | KMT2AMEN1ENPP2ENPP1ENPP3 | |
| SCHEMBL11569813 | 0.85 | MEN1 (0.68) | KMT2AMEN1ENPP2ENPP1ENPP3 | |
| SCHEMBL4321286 | 0.85 | MEN1 (0.68) | KMT2AMEN1ENPP2ENPP1ENPP3 | |
| SCHEMBL1665319 | 0.85 | ENPP1 (0.61) | KMT2AMEN1ENPP2ENPP1ENPP3 | |
| SCHEMBL687294 | 0.85 | KMT2A (0.72) | KMT2AMEN1ENPP2ENPP1ENPP3 | |
| SCHEMBL28490431 | 0.85 | KMT2A (0.72) | KMT2AMEN1ENPP2ENPP1ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117237-A | A kind of preparation method of aromatic nitriles or alkenyl nitrile compounds | 中国科学院上海有机化学研究所 | 2019-08-13 | — | — | CN | disclosed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |