Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867554 | 0.88 | ADORA2A (0.63) | ADORA2AMEN1MAPTKMT2A | |
| SCHEMBL6869736 | 0.88 | ADORA2A (0.48) | ADORA2AADORA3 | |
| SCHEMBL6871493 | 0.85 | ADORA2A (0.66) | ADORA2AADORA3SMN1; SMN2 | |
| SCHEMBL6871289 | 0.85 | ADORA2A (0.67) | ADORA2AADORA3 | |
| SCHEMBL6874155 | 0.84 | ADORA2A (0.72) | ADORA2AADORA3 | |
| SCHEMBL6868100 | 0.82 | ADORA2A (0.44) | ADORA2AMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6869222 | 0.82 | ADORA2A (0.72) | ADORA2AADORA3 | |
| SCHEMBL6863192 | 0.82 | ADORA2A (0.71) | ADORA2A | |
| SCHEMBL6870679 | 0.81 | ADORA2A (0.59) | ADORA2AKMT2A | |
| SCHEMBL6871736 | 0.81 | ADORA2A (0.69) | ADORA2AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |