Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873045 | 0.88 | ADORA2A (0.62) | ADORA2AMEN1MAPTKMT2A | |
| SCHEMBL6870096 | 0.85 | ADORA2A (0.60) | ADORA2AALDH1A1 | |
| SCHEMBL6863170 | 0.84 | ADORA2A (0.73) | ADORA2A | |
| SCHEMBL6873028 | 0.82 | ADORA2A (0.73) | ADORA2A | |
| SCHEMBL6868100 | 0.82 | ADORA2A (0.44) | ADORA2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL6870475 | 0.81 | ADORA2A (0.69) | ADORA2AALDH1A1POLBPKM | |
| SCHEMBL6870449 | 0.80 | RAB9A (0.45) | ADORA2AMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6870649 | 0.80 | ADORA2A (0.61) | ADORA2A | |
| SCHEMBL6867550 | 0.79 | ADORA2A (0.67) | ADORA2A | |
| SCHEMBL6873996 | 0.78 | ADORA2A (0.55) | ADORA2AALDH1A1POLBMAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |