Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 8/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.39 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 3/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687873 | 0.91 | PTGER3 (0.42) | PTGER3SLC16A3SLC16A1MCTS1CNR2 | |
| SCHEMBL687744 | 0.91 | PTGER3 (0.43) | PTGER3SLC16A3SLC16A1MCTS1CNR2 | |
| SCHEMBL687796 | 0.90 | CTSA (0.46) | PTGER3CNR2CTSASLC22A12MAPT | |
| SCHEMBL686799 | 0.90 | PTGER3 (0.51) | PTGER3CNR2CTSASLC22A12MAPT | |
| SCHEMBL687712 | 0.89 | PTGER3 (0.43) | PTGER3SLC16A3SLC16A1MCTS1CNR2 | |
| SCHEMBL688442 | 0.88 | PTGER3 (0.42) | PTGER3CNR2CTSASLC22A12MAPT | |
| SCHEMBL687045 | 0.87 | PTGER3 (0.42) | PTGER3CNR2CTSASLC22A12MAPT | |
| SCHEMBL688053 | 0.87 | PTGER3 (0.43) | PTGER3CNR2CTSASLC22A12MAPT | |
| SCHEMBL687802 | 0.87 | CTSA (0.34) | PTGER3CTSAITGB1ITGA4MEN1 | |
| SCHEMBL687640 | 0.86 | PTGER3 (0.40) | PTGER3SLC16A3SLC16A1CNR2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |