Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.39 |
| ▸ | WDR5 | P61964 | 2/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | IL1B | P01584 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688442 | 0.90 | PTGER3 (0.42) | CTSAMAPTPTGER3TP53RXFP1 | |
| SCHEMBL687045 | 0.90 | PTGER3 (0.42) | CTSAMAPTPTGER3CNR2SLC22A12 | |
| SCHEMBL687348 | 0.90 | PTGER3 (0.41) | CTSAMAPTTHRBPTGER3TP53 | |
| SCHEMBL688053 | 0.90 | PTGER3 (0.43) | CTSAMAPTPTGER3TP53ALDH1A1 | |
| SCHEMBL687873 | 0.89 | PTGER3 (0.42) | MAPTPTGER3WDR5CNR2SLC22A12 | |
| SCHEMBL687991 | 0.88 | GNRHR (0.38) | CTSAPTGER3CNR2 | |
| SCHEMBL686799 | 0.88 | PTGER3 (0.51) | CTSAMAPTTHRBPTGER3CNR2 | |
| SCHEMBL688170 | 0.87 | PTGER3 (0.41) | MAPTPTGER3TP53ALDH1A1RXFP1 | |
| SCHEMBL686986 | 0.87 | MEN1 (0.42) | CTSAMAPTPTGER3TP53MEN1 | |
| SCHEMBL687712 | 0.87 | PTGER3 (0.43) | CTSAMAPTPTGER3KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |