Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591393 | 1.00 | IDO1 (0.33) | IDO1TDO2SLC7A5PMP22SLC1A1 | |
| SCHEMBL686409 | 1.00 | IDO1 (0.33) | IDO1TDO2SLC7A5PMP22SLC1A1 | |
| SCHEMBL7375800 | 0.81 | IDO1 (0.36) | IDO1TDO2SLC7A5SLC1A1PTGS1 | |
| SCHEMBL7200966 | 0.80 | IDO1 (0.36) | IDO1TDO2SLC7A5SLC1A1PTGS1 | |
| SCHEMBL15156025 | 0.78 | IDO1 (0.35) | IDO1TDO2SLC7A5SLC1A1PTGS1 | |
| SCHEMBL1614569 | 0.78 | IDO1 (0.35) | IDO1TDO2SLC7A5SLC1A1PTGS1 | |
| SCHEMBL7241021 | 0.78 | IDO1 (0.35) | IDO1TDO2SLC7A5SLC1A1PTGS1 | |
| SCHEMBL4458615 | 0.77 | IDO1 (0.37) | IDO1TDO2SLC7A5SLC1A1PTGS1 | |
| SCHEMBL125177 | 0.76 | SLC1A3 (0.34) | IDO1TDO2SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL13857821 | 0.76 | SLC1A3 (0.34) | IDO1TDO2SLC1A1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572725-B1 | CHI-CONOTOXIN PEPTIDES HAVING A N-TERMINAL PYROGLUTAMIC ACID | XENOME LTD (AU) | 2012-02-29 | — | — | EP | disclosed |
| US-7851444-B2 | amino acid sequence containing Xaa1 Xaa2 Gly Val Cys Cys Gly Tyr Lys Leu Cys His Pro Cys SEQ ID NO. 3 where Xaa1 is a N-terminal pyroglutamate (pGlu) or D-pyroglutamate (DpGlu) residue; and Xaa2 is Asn or a deletion; prophylaxis; neuropathic pain, inflammation, incontinence, cardiovascular conditions | XENOME LTD. (AU) | 2010-12-14 | — | — | US | disclosed |
| EP-1572725-A4 | NOVEL CHI-CONOTOXIN PEPTIDES (-I) | XENOME LTD (AU) | 2008-09-24 | — | — | EP | disclosed |
| US-20060142201-A1 | Novel x-conotoxin peptides (-1) | XENOME LIMITED (AU) | 2006-06-29 | — | — | US | disclosed |
| EP-1572725-A1 | NOVEL CHI-CONOTOXIN PEPTIDES (-I) | Xenome Ltd (AU) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004050690-A1 | NOVEL χ-CONOTOXIN PEPTIDES (-I) | XENOME LTD (AU) | 2004-06-17 | — | — | WO | disclosed |