Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.35 |
| ▸ | GGT1 | P19440 | 4/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200966 | 0.87 | IDO1 (0.36) | IDO1TDO2PTGS1SLC7A11SLC7A5 | |
| SCHEMBL15156025 | 0.85 | IDO1 (0.35) | IDO1TDO2PTGS1SLC7A11SLC7A5 | |
| SCHEMBL1614569 | 0.85 | IDO1 (0.35) | IDO1TDO2PTGS1SLC7A11SLC7A5 | |
| SCHEMBL7241021 | 0.85 | IDO1 (0.35) | IDO1TDO2PTGS1SLC7A11SLC7A5 | |
| SCHEMBL4458615 | 0.84 | IDO1 (0.37) | IDO1TDO2PTGS1SLC7A11SLC7A5 | |
| SCHEMBL7371563 | 0.82 | PMP22 (0.36) | IDO1TDO2PTGS1SLC7A11SLC7A5 | |
| SCHEMBL686409 | 0.81 | IDO1 (0.33) | IDO1TDO2PTGS1SLC7A11SLC7A5 | |
| SCHEMBL5816605 | 0.81 | GRIN2D (0.37) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL687402 | 0.81 | IDO1 (0.33) | IDO1TDO2PTGS1SLC7A11SLC7A5 | |
| SCHEMBL7591393 | 0.81 | IDO1 (0.33) | IDO1TDO2PTGS1SLC7A11SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722436-A4 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | UNIV FLORIDA STATE (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0722436-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009833-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |