Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687402 | 1.00 | IDO1 (0.33) | IDO1TDO2SLC7A5PMP22SLC1A1 | |
| SCHEMBL686409 | 1.00 | IDO1 (0.33) | IDO1TDO2SLC7A5PMP22SLC1A1 | |
| SCHEMBL7375800 | 0.81 | IDO1 (0.36) | IDO1TDO2SLC7A5SLC1A1PTGS1 | |
| SCHEMBL7200966 | 0.80 | IDO1 (0.36) | IDO1TDO2SLC7A5SLC1A1PTGS1 | |
| SCHEMBL15156025 | 0.78 | IDO1 (0.35) | IDO1TDO2SLC7A5SLC1A1PTGS1 | |
| SCHEMBL1614569 | 0.78 | IDO1 (0.35) | IDO1TDO2SLC7A5SLC1A1PTGS1 | |
| SCHEMBL7241021 | 0.78 | IDO1 (0.35) | IDO1TDO2SLC7A5SLC1A1PTGS1 | |
| SCHEMBL4458615 | 0.77 | IDO1 (0.37) | IDO1TDO2SLC7A5SLC1A1PTGS1 | |
| SCHEMBL125177 | 0.76 | SLC1A3 (0.34) | IDO1TDO2SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL13857821 | 0.76 | SLC1A3 (0.34) | IDO1TDO2SLC1A1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244624-A1 | ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS | BTG INTERNATIONAL LIMITED (GB) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001044190-A1 | ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS | BTG INTERNATIONAL LIMITED (GB) | 2001-06-21 | — | — | WO | disclosed |