SCHEMBL6874393

SCHEMBL6874393

C[Si](C)(C(=O)O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
MAPT P10636 2/20 0.44
CES2 O00748 4/20 0.42
CES1 P23141 3/20 0.42
HPGD P15428 2/20 0.39
ALDH1A1 P00352 4/20 0.38
NAPRT Q6XQN6 3/20 0.38
TSHR P16473 2/20 0.38
DAO P14920 1/20 0.38
ALOX15 P16050 1/20 0.38
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA4 P22748 3/20 0.37
CA12 O43570 2/20 0.37
CA9 Q16790 2/20 0.37
CA14 Q9ULX7 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HMGB1 P09429 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16706156 0.84 ESR1 (0.44) ESR1ESR2MAPTCES2CES1
SCHEMBL27565431 0.82 ESR1 (0.48) ESR1ESR2MAPTCES2CES1
SCHEMBL5364559 0.80 MAPT (0.42) ESR1ESR2MAPTCES2CES1
SCHEMBL9937737 0.79 ESR1 (0.44) ESR1ESR2MAPTCES2CES1
SCHEMBL10863561 0.78 CES1 (0.48) ESR1ESR2MAPTCES2CES1
SCHEMBL5779320 0.75 ESR1 (0.41) ESR1ESR2MAPTCES2CES1
SCHEMBL28532520 0.75 ACHE (0.44) ESR1ESR2MAPTCES2CES1
SCHEMBL8406888 0.75 MAPT (0.42) ESR1ESR2MAPTCES2CES1
SCHEMBL17163820 0.72 CES1 (0.41) ESR1ESR2MAPTCES2CES1
SCHEMBL28992408 0.72 CES1 (0.41) ESR1ESR2MAPTCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104379636-B Polyimide resin and polyimide film produced from the same 可隆工业株式会社 2018-04-17 CN claimed
CN-107810222-A Polyamidoimide precursor, polyamidoimide film and the display device for including the polyamidoimide film 可隆工业株式会社 2018-03-16 CN claimed
CN-105940039-B Polyimide and film using the same 可隆工业株式会社 2018-02-16 CN claimed
CN-106536597-A High heat-resistant polyamic acid solution and polyimide film 可隆工业株式会社 2017-03-22 CN claimed
CN-105940039-A Polyimide and film using the same 可隆工业株式会社 2016-09-14 CN claimed
CN-104379636-A Polyimide resin and polyimide film produced from the same KOLON INC 2015-02-25 CN claimed
CN-117486920-A Gem difluoro allyl silicon compound and synthesis method thereof 云南铁峰矿业化工新技术有限公司 2024-02-02 CN disclosed
CN-109996839-A Polyimide film 宇部兴产株式会社 2019-07-09 CN disclosed
CN-109922956-A Laminate comprising polyimide film and hard conating 宇部兴产株式会社 2019-06-21 CN disclosed
CN-109923148-A Polyimides and the flexible device for having used the polyimides 宇部兴产株式会社 2019-06-21 CN disclosed
CN-109535423-A Polyimide precursor composition, the manufacturing method of polyimides, polyimides, polyimide film and substrate 宇部兴产株式会社 2019-03-29 CN disclosed
CN-105764991-B Polyimide precursor composition, method for producing polyimide, polyimide film, and substrate 宇部兴产株式会社 2018-10-26 CN disclosed
CN-108431136-A Polyimide material, method for producing same, and polyimide precursor composition used for production thereof 宇部兴产株式会社 2018-08-21 CN disclosed
CN-101827882-B Polyimide film with improved thermal stability KOLON INC 2014-04-30 CN disclosed
CN-103534294-A Polyimide precursor and polyimide UBE INDUSTRIES 2014-01-22 CN disclosed
WO-2012079583-A1 SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS AARHUS UNIVERSITET (DK) 2012-06-21 WO disclosed
CN-101827882-A Polyimide film with improved thermal stability KOLON INC 2010-09-08 CN disclosed
US-20040236130-A1 Process for the preparation of trialkylsilated carboxylate monomers, the obatined trialkylsilated carboxylate monomers and their use in anti-fouling coatings SIGMA COATINGS B.V. (NL) 2004-11-25 US disclosed
EP-1389214-A1 PROCESS FOR THE PREPARATION OF TRIALKYLSILYLATED CARBOXYLATE MONOMERS, THE OBTAINED TRIALKYLSILYLATED CARBOXYLATE MONOMERS AND THEIR USE IN ANTI-FOULING COATINGS SIGMA COATINGS B.V. (NL) 2004-02-18 EP disclosed
WO-2002094838-A1 PROCESS FOR THE PREPARATION OF TRIALKYLSILYLATED CARBOXYLATE MONOMERS, THE OBTAINED TRIALKYLSILYLATED CARBOXYLATE MONOMERS AND THEIR USE IN ANTI-FOULING COATINGS SIGMA COATINGS B.V. (NL) 2002-11-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040236130-A1 Process for the preparation of trialkylsilated carboxylate monomers, the obatined trialkylsilated carboxylate monomers and their use in anti-fouling coatings ACMSD, OR10J3, CFD ESR1 2214/4885ESR2 3643/4885MAPT 1423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.