Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27970512 | 0.84 | LMNA (0.53) | MAPTMEN1KMT2AGAAKDM4E | |
| SCHEMBL18801748 | 0.81 | PRMT6 (0.56) | MAPTMEN1KMT2AUSP2GAA | |
| SCHEMBL13383272 | 0.81 | CNR1 (0.50) | MAPTMEN1KMT2AUSP2GAA | |
| SCHEMBL13151154 | 0.81 | PRMT6 (0.51) | MAPTMEN1KMT2AUSP2GAA | |
| SCHEMBL23057208 | 0.79 | MEN1 (0.52) | MAPTMEN1KMT2AUSP2GAA | |
| SCHEMBL113800 | 0.79 | PRMT6 (0.58) | MAPTMEN1KMT2AUSP2GAA | |
| SCHEMBL6238716 | 0.78 | MEN1 (0.51) | MAPTMEN1KMT2AUSP2GAA | |
| SCHEMBL10377139 | 0.77 | SETD2 (0.54) | MAPTMEN1KMT2AUSP2GAA | |
| SCHEMBL22685038 | 0.77 | ALDH1A1 (0.59) | MAPTMEN1KMT2AUSP2GAA | |
| SCHEMBL17805419 | 0.77 | ALDH1A1 (0.50) | MAPTMEN1KMT2AUSP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821965-B1 | IMPORTANT IN DISEASE OR MEDICAL CONDITIONS SUCH AS INFLAMMATION AND IMMUNOREGULATION | ASTERZENECA AB (SE) | 2004-11-23 | — | — | US | disclosed |