SCHEMBL687459

SCHEMBL687459

COCc1ccc(CO)o1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.42
TDP1 Q9NUW8 3/20 0.42
TSHR P16473 2/20 0.42
DAO P14920 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
HPGD P15428 2/20 0.39
KDM4E B2RXH2 5/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 3/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
HTT P42858 2/20 0.34
CYP2A6 P11509 1/20 0.34
HSP90AA1 P07900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55096 0.88 DAO (0.38) ALDH1A1TDP1DAOSMN1; SMN2HPGD
SCHEMBL27859432 0.85 TDP1 (0.56) ALDH1A1TDP1TSHRSMN1; SMN2HPGD
SCHEMBL11816086 0.84 ALDH1A1 (0.37) ALDH1A1TDP1TSHRSMN1; SMN2HPGD
SCHEMBL13837723 0.83 ALDH1A1 (0.42) ALDH1A1TDP1TSHRDAOSMN1; SMN2
SCHEMBL17537995 0.81 ALDH1A1 (0.45) ALDH1A1TDP1TSHRDAOSMN1; SMN2
SCHEMBL183551 0.80
SCHEMBL19049630 0.79 ALOX5 (0.40) ALDH1A1TDP1DAOSMN1; SMN2HPGD
SCHEMBL631723 0.78 ALOX5 (0.46) ALDH1A1TDP1TSHRSMN1; SMN2HPGD
SCHEMBL17770842 0.78 CA2 (0.42) ALDH1A1TDP1TSHRDAOHPGD
SCHEMBL17693427 0.77 ALDH1A1 (0.42) ALDH1A1TDP1TSHRSMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10808328-B2 Selective oxidation of furan based alcohols via electro-generative process RHODIA OPERATIONS (FR) 2020-10-20 US claimed
US-20180363152-A1 SELECTIVE OXIDATION OF FURAN BASED ALCOHOLS VIA ELECTRO-GENERATIVE PROCESS SPECIALTY OPERATIONS FRANCE (FR) 2018-12-20 US claimed
EP-3391446-A1 SELECTIVE OXIDATION OF FURAN BASED ALCOHOLS VIA ELECTRO-GENERATIVE PROCESS Rhodia Operations (FR) 2018-10-24 EP claimed
US-9943903-B2 Binder composition for making self-hardening foundry molds, and method of producing foundry mold using the same KAO CORPORATION (JP) 2018-04-17 US claimed
EP-2752258-B1 ADHESIVE AGENT COMPOSITION FOR MOLD USED IN SELF-HARDENING MOLDING AND METHOD FOR PRODUCING MOLD USING THE SAME KAO CORP (JP) 2017-10-04 EP claimed
US-20140296372-A1 BINDER COMPOSITION FOR MAKING SELF-HARDENING FOUNDRY MOLDS, AND METHOD OF PRODUCING FOUNDRY MOLD USING THE SAME KAO CORPORATION (JP) 2014-10-02 US claimed
EP-2752258-A1 ADHESIVE AGENT COMPOSITION FOR MOLD USED IN SELF-HARDENING MOLDING AND METHOD FOR PRODUCING MOLD USING THE SAME Kao Corporation (JP) 2014-07-09 EP claimed
CN-115868661-A Preparation method and application of sweet and fragrant Maillard reaction product 江西中烟工业有限责任公司 2023-03-31 CN disclosed
CN-112512722-B Binder composition for mold making 花王株式会社 2023-02-28 CN disclosed
WO-2023021081-A1 VINYL ETHERS HENKEL AG & CO. KGAA (DE) 2023-02-23 WO disclosed
EP-4137485-A1 VINYL ETHERS Henkel AG & Co. KGaA (DE) 2023-02-22 EP disclosed
CN-109536466-B Aldehyde dehydrogenase, gene thereof, recombinant bacterium construction and application thereof in furan carboxylic acid synthesis 华南理工大学 2022-04-22 CN disclosed
CN-112512722-A Binder composition for mold making 花王株式会社 2021-03-16 CN disclosed
EP-0778095-B1 BINDER COMPOSITION FOR MOLD PRODUCTION AND PROCESS FOR PRODUCING MOLD KAO CORP (JP) 2007-02-21 EP disclosed
US-5932628-A BLEND OF SAND AND POLYFURFURAL ALCOHOL KAO CORPORATION (JP) 1999-08-03 US disclosed
EP-0778095-A1 BINDER COMPOSITION FOR MOLD PRODUCTION AND PROCESS FOR PRODUCING MOLD Kao Corporation (JP) 1997-06-11 EP disclosed
US-5616631-A CONTAINING FURAN DERIVATIVES AS CURING ACCELERATORS KAO CORPORATION (JP) 1997-04-01 US disclosed
EP-0698432-A1 Binder composition for mold making, binder/curing agent composition for mold making and sand composition for mold making Kao Corporation (JP) 1996-02-28 EP disclosed
US-5491180-A ACID CURABLE RESIN AND FURANDIMETHANOL DERIVATIVE AS CURING ACCELERATOR KAO CORPORATION (JP) 1996-02-13 US disclosed
US-5405865-A Pyrethroid esters ROUSSEL-UCLAF (FR) 1995-04-11 US disclosed