Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874763 | 1.00 | LMNA (0.43) | LMNASMN1; SMN2L3MBTL1THRBTDP1 | |
| SCHEMBL6872176 | 0.91 | LMNA (0.53) | LMNASMN1; SMN2L3MBTL1THRBTDP1 | |
| SCHEMBL6872189 | 0.91 | LMNA (0.53) | LMNASMN1; SMN2L3MBTL1THRBTDP1 | |
| SCHEMBL6875920 | 0.88 | ALDH1A1 (0.59) | LMNASMN1; SMN2L3MBTL1THRBTDP1 | |
| SCHEMBL6456166 | 0.88 | ALDH1A1 (0.53) | LMNASMN1; SMN2L3MBTL1THRBTDP1 | |
| SCHEMBL6456173 | 0.88 | ALDH1A1 (0.53) | LMNASMN1; SMN2L3MBTL1THRBTDP1 | |
| SCHEMBL6875914 | 0.88 | ALDH1A1 (0.59) | LMNASMN1; SMN2L3MBTL1THRBTDP1 | |
| SCHEMBL6877176 | 0.88 | TP53 (0.47) | LMNASMN1; SMN2L3MBTL1TDP1ALOX12 | |
| SCHEMBL6877168 | 0.88 | TP53 (0.47) | LMNASMN1; SMN2L3MBTL1TDP1ALOX12 | |
| SCHEMBL6457820 | 0.87 | ALDH1A1 (0.47) | LMNASMN1; SMN2THRBALOX12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |