Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875924 | 1.00 | MCHR1 (0.46) | MCHR1CNR1KCNH2AURKBNPC1 | |
| SCHEMBL6463074 | 0.92 | ALDH1A1 (0.48) | MCHR1CNR1KCNH2AURKBNPC1 | |
| SCHEMBL6463067 | 0.92 | ALDH1A1 (0.48) | MCHR1CNR1KCNH2AURKBNPC1 | |
| SCHEMBL6875466 | 0.89 | MCHR1 (0.50) | MCHR1CNR1KCNH2AURKBRAB9A | |
| SCHEMBL6875474 | 0.89 | MCHR1 (0.50) | MCHR1CNR1KCNH2AURKBRAB9A | |
| SCHEMBL6876830 | 0.89 | NPC1 (0.44) | MCHR1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6876838 | 0.89 | NPC1 (0.44) | MCHR1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6869293 | 0.87 | MCHR1 (0.46) | MCHR1 | |
| SCHEMBL6869286 | 0.87 | MCHR1 (0.46) | MCHR1 | |
| SCHEMBL6876048 | 0.87 | MCHR1 (0.46) | MCHR1NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |