Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 8/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447948 | 0.87 | NAMPT (0.40) | CTSLNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL5521755 | 0.86 | PRMT5 (0.42) | CASRCTSLNR1H4CTSSCTSB | |
| SCHEMBL6879222 | 0.85 | NR1H4 (0.43) | CTSLNR1H4NPC1MAPTRAB9A | |
| SCHEMBL6184516 | 0.84 | KDM4E (0.44) | CASRKDM4ENPC1MAPTRAB9A | |
| SCHEMBL6874225 | 0.81 | CASR (0.48) | CASRCTSLNPC1MAPTSMN1; SMN2 | |
| SCHEMBL6182405 | 0.80 | GAA (0.46) | KDM4EMAPTHPGD | |
| SCHEMBL6186860 | 0.80 | NPC1 (0.47) | CASRKDM4ENPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL6183907 | 0.78 | FAAH (0.46) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6182109 | 0.75 | CTSS (0.46) | CTSLCTSSCTSBCTSK | |
| SCHEMBL5530670 | 0.72 | HPGD (0.42) | CTSLNR1H4NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |