Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814457 | 0.80 | PBRM1 (0.39) | PDE4BS100A4CYP19A1PBRM1TDP1 | |
| SCHEMBL27795752 | 0.77 | KDM1A (0.34) | MEN1KMT2AALDH1A1CMA1AHR | |
| SCHEMBL6280501 | 0.73 | BACE1 (0.33) | PDE4BS100A4CYP19A1PBRM1TDP1 | |
| SCHEMBL6878453 | 0.70 | ESR2 (0.43) | PDE4BS100A4CYP19A1PBRM1TDP1 | |
| SCHEMBL484599 | 0.69 | PDE4B (0.46) | PDE4BS100A4PBRM1TDP1L3MBTL1 | |
| SCHEMBL27486590 | 0.69 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL31649883 | 0.68 | TDP2 (0.39) | L3MBTL1TDP2MEN1KMT2AALDH1A1 | |
| SCHEMBL445935 | 0.67 | MALT1 (0.41) | PDE4BS100A4PBRM1TDP1L3MBTL1 | |
| SCHEMBL30279114 | 0.67 | MALT1 (0.41) | PDE4BS100A4PBRM1TDP1L3MBTL1 | |
| SCHEMBL21332980 | 0.66 | PARP10 (0.50) | PDE4BS100A4TDP1L3MBTL1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825233-B2 | SUBSTITUTED BONZOIC ACID DERIVATIVES, USEFUL FOR PREVENTING AND/OR TREATING TUMORS, ARTHRITIS, AND NON-MALIGNANT SKIN DISORDERS | BRISTOL-MYERS SQUIBB COMPANY | 2004-11-30 | — | — | US | disclosed |
| US-20020193421-A1 | Compounds having retinoid-like activity | BRISTOL-MYERS SQUIBB COMPANY | 2002-12-19 | — | — | US | disclosed |
| WO-2002065984-A2 | COMPOUNDS HAVING RETINOID-LIKE ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193421-A1 | Compounds having retinoid-like activity | RARA, RARG, RARB | PDE4B 2332/4885S100A4 805/4885CYP19A1 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.