SCHEMBL687665

SCHEMBL687665

COc1c(C(=O)c2ccccc2)ccc(O)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.59
KDM4E B2RXH2 6/20 0.59
HSD17B10 Q99714 6/20 0.59
MAPK1 P28482 3/20 0.59
ALOX15 P16050 3/20 0.59
LMNA P02545 6/20 0.59
HTT P42858 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
NPSR1 Q6W5P4 1/20 0.59
ALDH1A1 P00352 7/20 0.58
HPGD P15428 6/20 0.58
CYP1A2 P05177 1/20 0.58
PGR P06401 1/20 0.58
CYP2D6 P10635 1/20 0.58
SLC6A2 P23975 1/20 0.58
PDE4A P27815 1/20 0.58
CYP2C19 P33261 1/20 0.58
HRH1 P35367 1/20 0.58
SLC6A3 Q01959 1/20 0.58
PDE4D Q08499 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6112746 0.98 MAPT (0.58) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL7767220 0.88 MAPT (0.60) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL25381912 0.87 MAPT (0.64) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL9339159 0.85 MAPT (0.77) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL19003473 0.83 HDAC1 (0.64) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL28716348 0.83 MAPT (0.55) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL480277 0.82 MAPT (0.60) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL27976994 0.82 MAPT (0.60) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL302637 0.81 LMNA (0.55) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL29709425 0.81 MAPT (0.59) MAPTKDM4EHSD17B10MAPK1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110739404-B Quantum dot light-emitting diode and preparation method thereof TCL科技集团股份有限公司 2021-04-02 CN claimed
CN-101316577-B Personal care compositions containing silicone resins with enhanced properties and methods of making and using the same MOMENTIVE PERFORMANCE MAT INC 2015-07-15 CN claimed
CN-101316577-A Personal care compositions containing silicone resins with enhanced properties and methods of making and using the same MOMENTIVE PERFORMANCE MAT INC (US) 2008-12-03 CN claimed
CN-1518469-A Dermatological preparations �����ɷ� 2004-08-04 CN claimed
CN-122005622-A Composition for improving, preventing or treating vaginitis or vulvitis comprising lactobacillus salivarius HHuMin-U 比菲德股份有限公司 2026-05-12 CN disclosed
US-12616730-B2 Topical composition comprising an extract of combined herbs comprising longanae arillus for the treatment or alleviation of skin ulcer and the use thereof MEDIHELPLINE CO., LTD (KR) 2026-05-05 US disclosed
CN-115337242-B Traditional Chinese medicine composition, extract, preparation method and application thereof, cosmetics and medicines 上海如妍化妆品有限公司 2025-03-21 CN disclosed
US-20250057872-A1 INNATE IMMUNOMODULATORY EFFECT OF GINSENG BERRY POLYSACCHARIDES IN IMMUNOCOMPROMISED CONDITIONS Gangneung-Wonju National University Industry Academy Cooperation Group (KR) 2025-02-20 US disclosed
US-20240398692-A1 MANUFACTURING METHOD OF COFFEE CELL AND ADVENTITIOUS ROOT CULTURE COMPRISING INCREASED BIOACTIVE SUBSTANCES AND USE THEREOF BIO-FD&C (KR) 2024-12-05 US disclosed
US-20240285714-A1 COMPOSITION FOR ANTI-INFLAMMATORY, ANTIOXIDANT, ANTI-WRINKLE OR HAIR HEALTH PROMOTION CONTAINING EXTRACT MIXTURE OF ZIZIPHUS JUJUBA MILLER, CITRUS UNSHIU PEEL AND ACORUS CALAMUS AS ACTIVE INGREDIENT INDUSTRY-ACADEMIC COOPERATION FOUNDATION DAEGU HAANY UNIVERSITY (KR) 2024-08-29 US disclosed
CN-118161520-A Lipolytic composition using surface-modified gas-generating nanoparticles 超新星生物有限公司 2024-06-11 CN disclosed
CN-115137664-B Cosmetic composition for improving skin activity containing Astragalus membranaceus peptide maturation matter 株式会社现代百朗德 2024-05-17 CN disclosed
EP-1438423-A1 ENZYME ACTIVITY INDICATORS Burton, Michael (GB) 2004-07-21 EP disclosed
WO-2004017982-A1 COMPOSITION COMPRISING THE EXTRACT OF ACTINIDIA ARGUTA AND RELATED SPECIES FOR THE PREVENTION AND TREATMENT OF ALLERGIC DISEASE AND NON-ALLERGIC INFLAMMATORY DISEASE PANGENOMICS CO., LTD (KR) 2004-03-04 WO disclosed
US-20040037909-A1 Composition comprising the extract of actinidia arguta and related species for the prevention and treatment of allergic disease and non-allergic inflammatory disease VIROMED CO., LTD. (KR) 2004-02-26 US disclosed
US-20030199660-A1 Silicone polymer, silicone composition, and cosmetic preparation containing the same SHIN-ETSU CHEMCIAL CO., LTD. (JP) 2003-10-23 US disclosed
WO-2003035900-A1 ENZYME ACTIVITY INDICATORS BURTON MICHAEL (GB) 2003-05-01 WO disclosed
EP-1291376-A1 SILICONE POLYMER, SILICONE COMPOSITION, AND COSMETIC PREPARATION CONTAINING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-03-12 EP disclosed
CN-1328813-A Cosmetics KYOWA HAKKO KOGY CO LTD (JP) 2002-01-02 CN disclosed
WO-1999062889-A1 NOVEL 8-AMINO-1,4-BENZOXAZINE COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ADIR ET COMPAGNIE (FR) 1999-12-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616730-B2 Topical composition comprising an extract of combined herbs comprising longanae arillus for the treatment or alleviation of skin ulcer and the use thereof CUTA, VEGFA, MMP8 MAPT 3161/4885KDM4E 2491/4885HSD17B10 3652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.