SCHEMBL6876920

SCHEMBL6876920

COC1O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](OCc2ccccc2)[C@H]1CO

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SSTR1 P30872 1/20 0.44
▸ SSTR2 P30874 1/20 0.44
▸ SSTR4 P31391 1/20 0.44
▸ SSTR3 P32745 1/20 0.44
▸ SSTR5 P35346 1/20 0.44
▸ PTPN1 P18031 7/20 0.41
▸ PTPN2 P17706 4/20 0.41
▸ LGALS3 P17931 1/20 0.41
▸ CDC25B P30305 5/20 0.40
▸ LGALS8 O00214 1/20 0.39
▸ BCHE P06276 1/20 0.38
▸ SLC6A2 P23975 1/20 0.38
▸ PTPN6 P29350 2/20 0.38
▸ PTPN11 Q06124 2/20 0.38
▸ GJB2 P29033 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28916072 0.88 SSTR1 (0.56) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL3155877 0.86 SSTR1 (0.53) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL24996978 0.83 SSTR5 (0.47) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL14490124 0.83 PTPN1 (0.44) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL3155871 0.83 SSTR5 (0.47) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL22677468 0.83 SSTR1 (0.52) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL22721951 0.78 SSTR1 (0.41) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL6667240 0.78 SSTR1 (0.56) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL18671706 0.78 SSTR1 (0.56) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL6890255 0.78 SSTR1 (0.48) SSTR1SSTR2SSTR4SSTR3SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6833361-B2 Compound for use in the treatment of viral diseases RIBAPHARM, INC. 2004-12-21 — — US disclosed
US-20030028013-A1 Novel nucleosides having bicyclic sugar moiety CEQUENT PHARMACEUTICALS, INC. 2003-02-06 — — US disclosed
US-6403566-B1 CONFORMATIONALLY LOCKED; ANTIVIRAL, ANTICANCER, STABILITY TO CELLULAR NUCLEASES AND STRONG BINDING AFFINITY TO NUCLEIC ACID TARGETS. ICN PHARMACEUTICALS, INC. 2002-06-11 — — US disclosed
EP-1082012-A4 NOVEL NUCLEOSIDES HAVING BICYCLIC SUGAR MOIETY ICN PHARMACEUTICALS (US) 2002-01-16 — — EP disclosed
EP-1082012-A1 NOVEL NUCLEOSIDES HAVING BICYCLIC SUGAR MOIETY ICN Pharmaceuticals, Inc. (US) 2001-03-14 — — EP disclosed
WO-1999060855-A1 NOVEL NUCLEOSIDES HAVING BICYCLIC SUGAR MOIETY ICN PHARMACEUTICALS, INC. (US) 1999-12-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030028013-A1 Novel nucleosides having bicyclic sugar moiety DCK, NUDT14, UCK2 SSTR1 3893/4885SSTR2 3595/4885SSTR4 2110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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