Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877173 | 1.00 | KMT2A (0.46) | KMT2AMAPK14LMNAALDH1A1ALOX12 | |
| SCHEMBL6876029 | 0.89 | LMNA (0.60) | KMT2AMAPK14LMNAALDH1A1ALOX12 | |
| SCHEMBL6876015 | 0.89 | LMNA (0.60) | KMT2AMAPK14LMNAALDH1A1ALOX12 | |
| SCHEMBL6877409 | 0.87 | KMT2A (0.56) | KMT2AMAPK14MEN1SMN1; SMN2CDK2 | |
| SCHEMBL6877414 | 0.87 | KMT2A (0.56) | KMT2AMAPK14MEN1SMN1; SMN2CDK2 | |
| SCHEMBL6872853 | 0.85 | EPHX2 (0.47) | KMT2AMAPK14MEN1SMN1; SMN2 | |
| SCHEMBL6872847 | 0.85 | EPHX2 (0.47) | KMT2AMAPK14MEN1SMN1; SMN2 | |
| SCHEMBL6872289 | 0.85 | KMT2A (0.47) | KMT2AMAPK14MEN1SMN1; SMN2KDM4E | |
| SCHEMBL6872291 | 0.85 | KMT2A (0.47) | KMT2AMAPK14MEN1SMN1; SMN2KDM4E | |
| SCHEMBL6873169 | 0.85 | MCHR1 (0.42) | KMT2AMAPK14MEN1SMN1; SMN2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |