Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460350 | 1.00 | ADRA2A (0.48) | ADRA2AMCHR1TUBB3BCHEACHE | |
| SCHEMBL6457252 | 0.90 | ADRA2A (0.51) | ADRA2AMCHR1TUBB3BCHEACHE | |
| SCHEMBL6876322 | 0.87 | ADRA2A (0.42) | ADRA2AMCHR1TUBB3BCHEACHE | |
| SCHEMBL6876315 | 0.87 | ADRA2A (0.42) | ADRA2AMCHR1TUBB3BCHEACHE | |
| SCHEMBL6873525 | 0.86 | KDM1A (0.43) | ADRA2AMCHR1TUBB3BCHEACHE | |
| SCHEMBL6873531 | 0.86 | KDM1A (0.43) | ADRA2AMCHR1TUBB3BCHEACHE | |
| SCHEMBL6873962 | 0.86 | ADRA2A (0.45) | ADRA2AMCHR1TUBB3BCHEACHE | |
| SCHEMBL6873966 | 0.86 | ADRA2A (0.45) | ADRA2AMCHR1TUBB3BCHEACHE | |
| SCHEMBL6876389 | 0.86 | MCHR1 (0.45) | ADRA2AMCHR1ACHENPY5R | |
| SCHEMBL6876384 | 0.86 | MCHR1 (0.45) | ADRA2AMCHR1ACHENPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |