Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.45 |
| ▸ | ACACB | O00763 | 7/20 | 0.40 |
| ▸ | ACACA | Q13085 | 6/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868859 | 0.94 | HSD11B1 (0.47) | MCHR1ADRA2ANPY5RACACBACACA | |
| SCHEMBL6878308 | 0.93 | MCHR1 (0.47) | MCHR1ADRA2ANPY5RACACBACACA | |
| SCHEMBL6866386 | 0.90 | HSD11B1 (0.48) | MCHR1ADRA2ANPY5RHSD11B1 | |
| SCHEMBL6866381 | 0.90 | HSD11B1 (0.48) | MCHR1ADRA2ANPY5RHSD11B1 | |
| SCHEMBL13793476 | 0.85 | MCHR1 (0.59) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6873253 | 0.84 | HSD11B1 (0.58) | MCHR1ADRA2AHSD11B1 | |
| SCHEMBL6873257 | 0.84 | HSD11B1 (0.58) | MCHR1ADRA2AHSD11B1 | |
| SCHEMBL6869049 | 0.84 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RACACBACACA | |
| SCHEMBL6869043 | 0.84 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RACACBACACA | |
| Hydrochloric Acid SCHEMBL6461571 | 0.83 | MAPK8 (0.46) | MCHR1ADRA2ANPY5RACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |